Lead Clinical Research
On time, On budget

Our Services

Clinical Operations

Sintesi Research acts as a partner for the whole spectrum of clinical investigations, with ad-hoc teams led by experienced Clinical Project Managers.


Sales, strategic initiatives, business partnerships, market development, business expansion, and marketing are all included in our activities.


Sintesi Research coordinates private investors working alongside VC  in Medical companies across Europe, Israel and US. 

Registration Distribution

We act as a distributor for third-party niche and specialty pharmaceutical products, Medical Device, Food Supplement, Drugs, Cosmetics.

Meet the Executive Team


Paolo De Simoni

Chief Executive Officer


Paolo is the founder of Sintesi Research Srl and since 2005 he is responsible for the overall management of the Company and Company’s operations including research and development. 

Paolo  brings more than 30 years of experience in the pharmaceutical industry and International CROs. 


Rachel Jacob

Chief Operation Officer
Marketing Director

Rachel has a vast experience of Business development and Marketing on a global level. She is CFO since 2013 and COO since 2018 at Sintesi Research Israel. 

Rachel is responsible for designing and implementing business operations as well as establishing policies that promote company culture and vision.


Alessandra Rimoldi

Businness Development Officer

Alessandra is a business development manager with 15 years of experience in researching solutions and new business opportunities worldwide.
She collaborates with cross-functional teams to improve customer service experience and needs.
Focused on building strong and dedicated client relationship and partnership, built on trust. 


Andrea Demartini

IT Manager

Andrea is responsible for IT solutions at Sintesi Research S.r.l. since 2016. He brings more than 20 years of IT experience, covering system management and maintenance, b2b assistance, retail assistance, network management and system building.

Our Skills

  • Programs customization.
  • Highly flexible approach to clinical research, from selected regional services to full-service international studies.
  • Particular care to the ethical nature and transparency of each implemented procedure to ensure an elevated reliability of the study outcomes
  • Experienced/dedicated project team
  • Implementation of web-based networks, able to meet each client request and to grant access to relevant trial-related information, updates on project status, newsletters, reports and databases.


Sintesi Research joins and integrates professionals inside a group of Companies established from capitalization of competence and business opportunity matured over the years.

  • Sintesi InfoMedica is a multimedia publishing company, dedicated to pharmaceutical market, offering a broad range of products and services, presented in both traditional printed and the latest electronic media formats or a combination of the two. Sintesi InfoMedica is committed to lead each project from conception to delivery in a timely and cost efficient way. Or, when needed, picking up a project in any work phase to meet the clients emerging needs.

“Every client is a “new” client for us. We execute every project with the utmost attention to details, and uncompromised focus on quality which has earned us the confidence and trust of national and international biotechnology and pharmaceuticals companies.” 

Paolo De Simoni

Sintesi Research is a Contract Research Organization headquartered in Milan, with regional offices in Tel-Aviv (Israel) and international strategic partnerships, offering full support in planning, managing and evaluating Phase I-IV Clinical Trials.

We provide fully therapeutic areas expertise at all levels and across each field involved in the product development process.